Small Intestinal Bacterial Overgrowth Treatment in Indore

Dr. Bansal's Gastro Clinic, Indore

Small Intestinal Bacterial Overgrowth (SIBO) – Description

SIBO, Small Intestinal Bacterial Overgrowth, is a condition defined by an abnormal increase in the number of bacteria within the small intestine, mostly those bacteria that are localised in the colon. The normal physiological state of the small intestine includes relatively low bacterial counts. In SIBO, this balance is disrupted, leading to malabsorption and gastrointestinal symptoms. Such impaired gut motility, certain structural abnormalities, or specific diseases can cause it. If SIBO is left unmanaged, nutrient deficiencies, weight loss, and chronic digestive problems may ensue.

Types of SIBO

SIBO can be categorised by either the dominant type of gas produced by bacteria or its underlying cause:

1. Hydrogen-Dominant SIBO

Bacteria produce primarily hydrogen gas.

Commonly associated with diarrhoea-predominant symptoms.

2. Methane-Dominant SIBO

Bacteria produce mainly methane gas, often from archaea in the gut.

Usually associated with constipation-predominant symptoms.

3. Hydrogen-Methane Mixed SIBO

Both hydrogen and methane gases are produced.

Symptoms include alternating diarrhoea and constipation.

4. According to the Underlying Cause

Motility-related SIBO: due to conditions such as diabetes, scleroderma, or post-surgical changes that slow gut motility.

Anatomical SIBO: This is due to strictures, diverticula, or blind loops in the small intestine.

Immune-related SIBO due to immunodeficiency or chronic diseases that affect gut flora.

Symptoms of SIBO

Bloating and abdominal distension

Excessive gas and belching

Diarrhoea or constipation, depending on the type of gas

Abdominal pain or cramping

Nausea

Fatigue or unintentional weight loss in chronic cases

Malnutrition or deficiencies in vitamins (B12, fat-soluble vitamins)

Treatment of SIBO

Antibiotics

Rifaximin is commonly used; other antibiotics may be prescribed depending on the gas type and symptoms.

Dietary Management

Low FODMAP diet or specific carbohydrate restriction to reduce bacterial fermentation.

Treat Underlying Causes

Correct gut motility issues or structural problems.

Probiotics and Nutritional Support

May help restore healthy gut flora.

Supplement vitamins and minerals if deficiencies are present.

Lifestyle Measures

Eat smaller, more frequent meals.

Chew food properly.

Prevention of SIBO
1. Maintain Healthy Gut Motility

Aerobic exercise

Manage conditions that affect gut motility, including diabetes or hypothyroidism

2. Avoid Unnecessary Antibiotics

Overuse can disrupt normal gut flora and increase SIBO risk.

3. Balanced Diet

Avoid excessive sugar and highly processed foods

Include fibre gradually to support a healthy microbiome.

4. Address Underlying Conditions

Treat chronic illnesses: Crohn's disease, celiac disease

Correct any structural abnormalities surgically when needed

5. Periodic Monitoring: Individuals with recurrent SIBO or predisposing conditions should be evaluated periodically